Hillar Klandorf, Ph.D., Associate Professor
E-Mail:<hkland@wvu.edu>
Education:
Summary of Interests:
My research is directed towards investigating why birds live longer
than comparably-sized mammals. Birds have higher metabolic rates and higher
body temperatures than mammals and are naturally hyperglycemic. These
factors should cause an acceleration in the rate of aging, yet this is not
the case. Current research in my laboratory involves the determination of
the presence and rate of accumulation of certain markers of tissue aging,
the effect of various dietary supplements on the rate of tissue aging, and
the possible interaction of uric acid as an antioxidant and the resistance
of birds to the detrimental effects of their hpyperglycemia. We are also
using this methodology to estimate the chronological age of non-domesticated
species of birds.
Graduate Research Assistantships are available.
Some Relevant Publications:
- Pinchasov, Y., Galili, D., Yonash, N., David, G., and Klandorf, H. (1993)
Effect of feed restriction by ad libitum-fed self-restricting diets on
subsequent performance of broiler breeder hens. Poult. Sci.
72:613-619.
- Klandorf, H., Holt, S., McGowan, J., Pinchasov, Y., Deyette, D., and
Peterson, R. (1995). Hyperglycemia and non-enzymatic glycation of
serum and tissue protiens in chickens. Comp. Biochem. Physiol.
110C:215-220.
- Qin, X., and Klandorf, H. (1995). Effect of estrogen on egg
production, shell quality, and calcium metabolism in molting hens.
Comp. Biochem. Physiol. 110:55-59.
- Klandorf, H., Zhou, Q., and Sams, A. (1996). Inhibition of aminoguanidine of glucose-derived collagen cross-linking in skeletal muscle of broiler breeder hens. Poult. Sci. 75:432-437
- Klandorf, H., Boyce, C.S., Killefer, J., McGowan, J.A., Peterson, R.A.,
Valent, M., and Deaver, D.A. (1997). The effect of photoperiod and food
intake on daily changes in plasma calcitonin on broiler breeder hens.
Gen. Comp. Endocrinol. In Press.
- Iqbal, M., Probert, L.L., and Klandorf, H. (1997) Effect of
aminoguanidine on tissue pentosidine and production in broiler breeder
hens. Poult. Sci. In press.
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